Which symptoms can indicate local effects of pesticide exposure?

Symptoms such as rash, discoloration, and burning of the eyes or throat indicate local effects of pesticide exposure because they are typically associated with direct contact or irritation at the site of exposure. These symptoms demonstrate how the pesticide acts on local tissues and potentially cause immediate discomfort or harm without necessarily affecting the entire body systemically. Local effects are characterized by their immediacy and site-specific manifestations, contrasting with systemic effects, which would involve broader physiological responses that can occur after absorption into the bloodstream. This understanding is crucial for pesticide applicators to identify and respond to exposure incidents effectively, safeguarding both public health and the environment.